srebp processing Search Results


magnetic protein a g  (MedChemExpress)
93
MedChemExpress magnetic protein a g
Magnetic Protein A G, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/srebp+processing/SREBP-1+Antibody/pm40263296-241-5-8
Average 93 stars, based on 1 article reviews
magnetic protein a g - by Bioz Stars, 2026-10
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pdgfc regulation  (TargetMol)
92
TargetMol pdgfc regulation
Figure 5. PDGFC regulates <t>SREBP1</t> via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level
Pdgfc Regulation, supplied by TargetMol, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/srebp+processing/Anti-SREBP1+Polyclonal+Antibody/pm39225567-150-11-25
Average 92 stars, based on 1 article reviews
pdgfc regulation - by Bioz Stars, 2026-10
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srebp 2  (Boster Bio)
93
Boster Bio srebp 2
Figure 5. PDGFC regulates <t>SREBP1</t> via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level
Srebp 2, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/srebp+processing/Anti-SREBF2+Antibody/pmc12339905-88-61-65
Average 93 stars, based on 1 article reviews
srebp 2 - by Bioz Stars, 2026-10
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srebp 1c  (Shanghai Korain Biotech Co Ltd)
94
Shanghai Korain Biotech Co Ltd srebp 1c
Figure 5. PDGFC regulates <t>SREBP1</t> via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level
Srebp 1c, supplied by Shanghai Korain Biotech Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/srebp+processing/Rat+Sterol+Regulatory+Element-binding+Protein+1C/pm38727800-90-31-61
Average 94 stars, based on 1 article reviews
srebp 1c - by Bioz Stars, 2026-10
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srebp 2  (Shanghai Korain Biotech Co Ltd)
94
Shanghai Korain Biotech Co Ltd srebp 2
Figure 5. PDGFC regulates <t>SREBP1</t> via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level
Srebp 2, supplied by Shanghai Korain Biotech Co Ltd, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/srebp+processing/Mouse+Sterol+Regulatory+Element-binding+Protein+2/pm38727800-90-35-61
Average 94 stars, based on 1 article reviews
srebp 2 - by Bioz Stars, 2026-10
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Image Search Results


Figure 5. PDGFC regulates SREBP1 via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Article Title: Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism.

doi: 10.1002/advs.202407069

Figure Lengend Snippet: Figure 5. PDGFC regulates SREBP1 via PI3K/AKT signaling pathway to promote lipid biosynthesis. A) GO molecular function enrichment of DEGs in BxPC-3 cells silencing PDGFC or not. B) The mRNA level of SREBF1 between PDAC tumor tissue or normal tissue in GEPIA2 database. C) The mRNA level of SREBF1 after PDGFC silencing in SW1990 cells. D) KEGG enrichment of DEGs after PDGFC silencing or not. E) GSEA enrichment results suggest PI3K/AKT signaling pathway is the downstream target of PDGFC. F) The protein level of PDGFR/PI3K/AKT signaling pathway and SREBP1 after PDGFC silencing were confirmed by western blotting. G) The mRNA level of SREBF1 after capivasertib treatment in PDAC cells. H) The protein level

Article Snippet: To further elucidate the pivotal role of PI3K/AKT signaling pathway in PDGFC regulation of SREBP1, we treated PDAC cells with capivasertib, a specific AKT inhibitor (TargetMol, Shanghai, China).

Techniques: Western Blot

Figure 6. PDGFC facilitates PDAC progression by upregulating SREBP1 expression. A) The mRNA and protein level after SREBF1 overexpression in BxPC-3 and SW1990 cells. B) Cell growth curve after SREBF1 overexpression in PDAC cells. C) Cell migration and invasion ability after SREBF1 overex- pression in BxPC-3 cells. D) Cell migration and invasion ability after SREBF1 overexpression in SW1990 cells. E) The mRNA level after PDGFC silencing and PDGFC silencing with SREBF1 overexpression confirmed by RT-qPCR. F) The protein level after PDGFC silencing and PDGFC silencing with SREBF1 overexpression confirmed by western blotting. G) Cell growth curve after PDGFC silencing and PDGFC silencing with SREBF1 overexpression. H) Sta- tistical analysis of cell migration and invasion ability. I) Representative images of cell migration and invasion ability in BxPC-3 and SW1990 cells. Data are presented as mean ± SD (n = 3). *p < 0.05; **p < 0.01; ***p < 0.001 according to Student’s t-test.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Article Title: Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism.

doi: 10.1002/advs.202407069

Figure Lengend Snippet: Figure 6. PDGFC facilitates PDAC progression by upregulating SREBP1 expression. A) The mRNA and protein level after SREBF1 overexpression in BxPC-3 and SW1990 cells. B) Cell growth curve after SREBF1 overexpression in PDAC cells. C) Cell migration and invasion ability after SREBF1 overex- pression in BxPC-3 cells. D) Cell migration and invasion ability after SREBF1 overexpression in SW1990 cells. E) The mRNA level after PDGFC silencing and PDGFC silencing with SREBF1 overexpression confirmed by RT-qPCR. F) The protein level after PDGFC silencing and PDGFC silencing with SREBF1 overexpression confirmed by western blotting. G) Cell growth curve after PDGFC silencing and PDGFC silencing with SREBF1 overexpression. H) Sta- tistical analysis of cell migration and invasion ability. I) Representative images of cell migration and invasion ability in BxPC-3 and SW1990 cells. Data are presented as mean ± SD (n = 3). *p < 0.05; **p < 0.01; ***p < 0.001 according to Student’s t-test.

Article Snippet: To further elucidate the pivotal role of PI3K/AKT signaling pathway in PDGFC regulation of SREBP1, we treated PDAC cells with capivasertib, a specific AKT inhibitor (TargetMol, Shanghai, China).

Techniques: Expressing, Over Expression, Migration, Quantitative RT-PCR, Western Blot